Pomegranate Seed Oil – Punicic Acid

Pomegranate

Pomegranate Seed Oil

A single drop of its precious oil, pressed from the seeds found in the red arils of the fruit. Rich in rare Omega 5 essential fatty acid, it is the only known botanical source of Conjugated Linolenic Acid (CLnA), also known as Punicic Acid, one of the more potent antioxidants known to modern science, and a natural phytoestrogen (plant-based estrogen).

In lab rats, it was found that punicic acid was converted to the CLA rumenic acid (9Z11E-CLA).In vitro, it shows  OLETF rats—a strain which becomes obese—remained relatively lean when punicic acid was added to their feed.

Pomegranate (Punica granatum) pure chemicals show possible synergistic inhibition of human PC-3 prostate cancer cell invasion across Matrigel™

  • Ephraim Philip Lansky 
  • , Gregory Harrison
  • , Paul Froom
  • , Wen G. Jiang

Four pure chemicals, ellagic acid (E), caffeic acid (C), luteolin (L) and punicic acid (P), all important components of the aqueous compartments or oily compartment of pomegranate fruit (Punica granatum), and each belonging to different representative chemical classes and showing known anticancer activities, were tested as potential inhibitors of in vitro invasion of human PC-3 prostate cancer cells in an assay employing Matrigel™ artificial membranes. All compounds significantly inhibited invasion when employed individually. When C, P, and L were equally combined at the same gross dosage (4 μ g/ml) as when the compounds were tested individually, a supradditive inhibition of invasion was observed, measured by the Kruskal-Wallis non-parametric test.

 

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